In addition to somatic and infectious diseases that are common among people on the human organism to have adverse health effects social (lack of and poor nutrition, housing, occupational hazards), environmental factors, medical interventions (surgery, stress, etc.), in which primarily affected the immune system, there are secondary immunodeficiencies. Despite continuous improvement techniques and tactics pursued basic therapy of diseases and the use of drugs deep reserve with the involvement of medical methods do not impact the effectiveness of treatment remains sufficiently low level. Often the cause of these features in the development, course and outcome of disease is the presence of patients with certain disorders of the immune system. Studies conducted in recent years many countries, allowed to develop and implement a broad clinical practice new integrated approaches to the treatment and prevention of various nosological forms of diseases, using drugs immunotropic directed action based on the level and extent of violations of the immune system. An important aspect in the prevention of relapses and treatment of diseases, as well as in the prevention of immunodeficiency, is a combination of basic therapy with rational immune correction. At present, one of the most urgent tasks is to develop immunopharmacology of new drugs, which combine the essential characteristics such as efficacy and safety application. (Not to be confused with Coen brothers!). Immunity and the immune system.
Immunity – to protect the body from foreign agents genetically exogenous and endogenous origin, aimed at preserving and maintaining genetic homeostasis, its structural, functional, biochemical and antigenic integrity of the individual. Immunity is one of the most important characteristics of all living organisms, created in the process of evolution. The principle of operation of protective mechanisms is the recognition, treatment and elimination of foreign bodies. Protection by means of two systems – non-specific (innate, natural) and specific (acquired) immunity. These two systems represent two stages of a single process of defense. Nonspecific immunity acts as a first line of defense and as its final stage, and the system of acquired immunity does intermediate features specific to recognize and memorize a foreign agent and the connection of powerful innate immunity at the final stage of the process.